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Search Results for " mglur5 inhibitor "

7

Compounds

Cat No. Product Name Synonyms Targets
T6457 CTEP mGluR5 inhibitor,RO 4956371 GluR
CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.
T22641 CDPPB GluR
CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
T23514 VU-1545 VU 1545 GluR
VU-1545 is mGlu5 positive allosteric modulator.
T2053 ADX-47273 BA 94673139 GluR
ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
T11393 GET73 Gamma hydroxybutyric acid analogue,GET 73 GluR
GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
T3479 (RS)-MCPG alpha-MCPG,(±)-MCPG GluR
(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.
T81801 mGluR5 antagonist-1
mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].
TargetMol