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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6457 | CTEP | mGluR5 inhibitor,RO 4956371 | GluR |
CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors. | |||
T22641 | CDPPB | GluR | |
CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5). | |||
T23514 | VU-1545 | VU 1545 | GluR |
VU-1545 is mGlu5 positive allosteric modulator. | |||
T2053 | ADX-47273 | BA 94673139 | GluR |
ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM). | |||
T11393 | GET73 | Gamma hydroxybutyric acid analogue,GET 73 | GluR |
GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. | |||
T3479 | (RS)-MCPG | alpha-MCPG,(±)-MCPG | GluR |
(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist. | |||
T81801 | mGluR5 antagonist-1 | ||
mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1]. |